Professor Adam Woolley At BYU: Research, 3D Printing & Biomolecules

Could the microscopic world hold the keys to unlocking breakthroughs in medicine, diagnostics, and materials science? Adam T. Woolley, a distinguished professor at Brigham Young University, is dedicating his career to exploring precisely this intersection of miniaturization and biomolecules, paving the way for potentially revolutionary advancements.

At the heart of Professor Woolley's research lies a fascinating concept: the interrelationship between biological molecules and miniaturization. This isn't just a recent focus; it's a sustained area of investigation that has spanned years, yielding significant contributions to the scientific community. His work, housed within the Department of Chemistry and Biochemistry at Brigham Young University (BYU) in Provo, Utah, pushes the boundaries of what's possible at the nanoscale. He is at the forefront of this field and continues to drive innovation in this promising field.

Category Details
Full Name Adam T. Woolley
Current Affiliation Professor, Department of Chemistry and Biochemistry, Brigham Young University, Provo, Utah, USA
Education B.S. in Chemistry, Brigham Young University (Summa Cum Laude, 1992)
Research Focus Miniaturization and Biomolecules, 3D-printed microfluidics, analytical systems for bacteria identification, Bioanalysis
Awards and Recognition Recipient of the 2007 Award for Young Investigators in Separation Science
Editorial Roles Former Chair Editor of Analytical and Bioanalytical Chemistry (ABC) (July 2017 June 2023), continuing with regular editorial responsibilities.
Key Publications
  • Past, Current, and Future Roles of 3D Printing in the Development of Capillary Electrophoresis Systems. (Trac Trends in Analytical Chemistry 2023)
  • Development of immunoaffinity monoliths for extraction of preterm birth biomarkers from blood serum in 3D printed microfluidic devices. (Journal of the Association for Laboratory Automation 2010)
  • Numerous other publications in the field of analytical chemistry and bioanalysis.
Areas of Expertise Microfabrication, microfluidic systems, biomolecule analysis, analytical chemistry, 3D printing in analytical applications.
Contact
  • Woolley Analytical Lab Site
  • Department of Chemistry and Biochemistry, C100 BNSN, Brigham Young University, Provo, UT 84602
  • Simmons Center for Cancer Research, Brigham Young University, 261 MCDB Provo, UT 84602
  • General office hours by appointment.
Reference Website Brigham Young University Website

Professor Woolley's work extends beyond mere observation; he actively designs and builds. His lab is known for applying microfabrication techniques to create sophisticated microfluidic systems. This involves creating miniature devices, often using 3D printing, to manipulate and analyze tiny amounts of fluids and biological samples. These systems are then used for a variety of applications, including the analysis of bacteria. One of the noteworthy contributions of his lab is the development of microfluidic setups capable of incubating and detecting bacterial growth in a relatively short timeframe of approximately two hours. This advancement holds the potential to accelerate diagnoses and improve patient outcomes.

The scope of his research encompasses a wide array of innovative projects. One area of focus involves the application of 3D printing, an emerging technology that offers the potential to overcome limitations in traditional analytical methods. 3D printing allows for the creation of complex, customized microfluidic devices that can be precisely tailored for specific analytical tasks. The application of 3D printing opens up new possibilities in various fields of research, including biomarker detection and analytical systems. This technology is a core component of Professor Woolley's current research, which focuses on 3D-printed integrated microfluidics for biomarker measurement and the development of analytical systems for identifying bacteria.

A key aspect of Professor Woolley's research is the design of controlled nanoscale structures using DNA. His team skillfully folds DNA into defined designs, creating functional electronic elements after purification and metallization. This approach leverages the unique properties of DNA to construct incredibly small and precise structures, opening doors to new materials and devices. It exemplifies the innovative fusion of biology and engineering that defines his work.

Professor Woolley's contributions have earned him recognition, including the 2007 Award for Young Investigators in Separation Science. His dedication to the field is also evident in his role as the chair editor of Analytical and Bioanalytical Chemistry (ABC). During his tenure from July 2017 to June 2023, he led ABC as its first chair editor. Now, he continues to serve with ongoing editorial responsibilities, further solidifying his influence in the scientific community.

The significance of his research is multifaceted. The development of efficient and accurate methods for analyzing bacteria is critical in the fight against antimicrobial resistance, a global health crisis with millions of deaths attributed to it annually. Current analytical tools often face limitations, leading to delayed diagnoses and potentially hindering effective treatment. Professor Woolley's development of rapid detection methods, for example, utilizing microfluidic setups, directly addresses this challenge. This is essential to timely medical interventions.

The applications of his research extend beyond the clinical realm. His work on microfluidic systems and the analysis of biological molecules holds potential for various fields, including environmental monitoring, food safety, and drug discovery. As a professor in BYUs Department of Chemistry and Biochemistry, he continues to be a driving force in the exploration of this dynamic, rapidly evolving field.

His work is not solely confined to his laboratory. Students and colleagues at Brigham Young University collaborate with Professor Woolley on various projects. Several individuals, including Pamela N. Nge, Chad I. Rogers, Yesman Akuoko, Anum Tahir, Wei Wang, Nicholas A. Chartrand, and others, have contributed to publications and research efforts under his supervision and collaboration. This collaborative spirit amplifies the impact of his work and helps to advance the field.

The physical location of the research is at Brigham Young University, specifically in the Department of Chemistry and Biochemistry, located in Provo, Utah, USA. The Simmons Center for Cancer Research at BYU also serves as a location where some of his research activities are conducted. The integration of these physical spaces, along with his team's collective expertise, provides a stimulating environment for research and scholarly exchange.

The overall trajectory of his work points towards a future where miniaturization and biomolecules converge to offer innovative solutions to complex challenges. Professor Woolley's research is a testament to the power of interdisciplinary approaches in solving complex scientific problems. His contributions continue to make a significant impact on the fields of analytical chemistry and bioanalysis.

In summary, Adam T. Woolley's work stands as a testament to the innovative power of combining miniaturization with biomolecules. His research, rooted in the Department of Chemistry and Biochemistry at Brigham Young University, is poised to make important contributions to medical diagnostics, and numerous other fields. His commitment to exploring the microscopic world and pushing the boundaries of analytical chemistry will continue to inspire and shape the landscape of scientific discovery for years to come.

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